The Evidence synthesis paper will be a 10 page paper in APA format (excluding title page, references and appendix—abstract not needed) that will form the second section of your scholarly examination of the clinical problem from your Background & Significance paper. You may use portions of your Background & Significance paper as appropriate to your topic. Remember to keep your PICOT in mind when developing this paper. This paper will help set the foundation for your clinical project and provide ample evidence to the nature and urgency of the need to address your chosen PICOT problem. You must Include an APPENDIX with strict APA guidelines with a Matrix table of relevant research articles (10 articles total in the matrix table; you may use 5 relevant references from your Background and significance paper).